CAPATI ~ESPIRITU, Darlene Jane WN. June 2022. DISTRIBUTION AND TRANSMISSION PATTERN OF SARS-CoV-2 IN THE MUNICIPALITY OF MAGALANG, PAMPANGA, Pampanga State Agricultural University, Magalang, Pampanga. Adviser: Dr. Michael Angelo C. Nicdao The Municipality of Magalang confirmed local transmission of CoViD-19 on April 17, 2020. CoViD-19 cases with positive real-time reverse transcription-polymerase chain reaction (RT-PCR) were studied for their characteristics and epidemiological time-to-event distributions. Data are requested from the Municipal Health Officer of Magalang, Pampanga with the recorded 1,709 confirmed cases from the first case up to December 31, 2021. In this research, the distribution and transmission pattern of SARS-CoV-2 in the population of Magalang, Pampanga, as well as the epidemiological profile, source of infection, comorbidity, and mortality of CoViD-19 were analyzed. The age group with the highest number of cases (420) was recorded as 21-30 years old and the lowest was in the age group of 90-99 (6 cases). The males and the females were more or less of the same percentage distribution. Based on residency Barangay San Isidro had the most cases with 15.8% (270 cases) and with a population density of 117.91, and Barangay Escaler had the least cases with 0.53% (9 cases) with a population density of 15.82. From the month of April to October 2021, the number of cases remained persistently high, with the greatest death rate with a fatality rate of 6.44%. Cough and dyspnea are the most prevalent onset symptoms in mortality cases. Moreover, the age of confirmed cases has a positive correlation with mortality; however, there is no correlation between sex and mortality as well as residency and mortality. In the transmission of SARS-CoV-2, most of the infected are from an unknown source. It is a negative correlation that the increase in mortality is due to an unknown source of infection. In addition, comorbidity and mortality of CoViD-19 cases are positively correlated. The findings will be beneficial in public health management and will serve as a record for the CoViD-19 Pandemic. Keywords: CoViD-19, SARS-CoV-2, Confirmed cases Master of Science in Biology July 2022.