TALLEDO, REYNALYN F., Department of Resource Engineering and Agricultural Mechanization, College of Engineering and Computer Studies, Pampanga State Agricultural University, Magalang, Pampanga. August, 2022. "Optimization of Spray Drvin Performance of Jackfruit 4rtoca :us Hetero:h-llus Lam Leaves Usin Response Surface Methodology". Adviser. Dr. Mari Rowena C. Tanquilut This study was conducted at the Bio-Resource Processing Center of the College of Engineering and Computer Studies (CoECS), Pampanga State Agricultural University, from Apnil to July 2022. Jackfruit (Artocarpus heterophyilus Lam) \eaf powder was produced using a spray dryer and response surface methodology was used to optimize the operating conditions of spray drying. The independent variables were inlet temperature, maltodextrin and concentration ratio of leaves, while drying experiments were carried out with an inlet temperature range of 85-95°C, maltodextrin range of 10-20°o and concentration ratio of leaves is to water (1:4, 1:6, and 1:8). The responses were moisture content (MC), drying capacity (DC) and recovery rate (RR) of the spray drying process. It aimed to determine the optimum condition of spray drying using jackfruit leaves. The investigation was carried out by using response surface methodology and the process conditions were optimized by using this method. Optimum operating conditions were found to be an inlet drying temperature of 90°C, concentration ratio (1 leaves:5.672 water), and 18.759% maltodextrin with a predicted DC (6.84 kg hr), MC (6.59% 0), and RR (0.33 kg/hr). The comparison of the predicted and actual has no significance. At this optimum condition, toxicity screening found to be 100°o safe at any amount of spray dried jackdruit leaf powder, sensory evaluation found to be as very much like with respect to the taste, aroma, color, astringency, and general acceptability, nutrients analysis found that crude protein content has 5.72% and ash content has 1.70°e in every 1 gram of spray dred jackfruit leaf powder, shelf life analysis found that treatment 1, 2,3 and 4 has no significant changes during the two-week storage period in terms of color, aroma, texture, and no presence of molds detected and cost analysis found that the product spray dried jackfruit leaf powder determined to be economically viable at Php 530.00 per kg.