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Hypocholesterolemic effect of spray-dried extracts of yacon (Smallanthus sonchifolius) roots and okra (Abelmoschus esculentus) leaves on cholesterol-fed mice (Record no. 15430)

MARC details
000 -LEADER
fixed length control field 02061ntm a2200169 a 4500
001 - CONTROL NUMBER
control field 134232
003 - CONTROL NUMBER IDENTIFIER
control field 0000000000
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250408094531.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 230117n 000 0 eng d
100 0# - MAIN ENTRY--PERSONAL NAME
Personal name Guzman, Ira Allyssa M.
245 00 - TITLE STATEMENT
Title Hypocholesterolemic effect of spray-dried extracts of yacon (Smallanthus sonchifolius) roots and okra (Abelmoschus esculentus) leaves on cholesterol-fed mice
Medium [manuscript] /
Statement of responsibility, etc. Ira Allyssa M. Guzman.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. Magalang, Pampanga :
Name of publisher, distributor, etc. Pampanag State Agricultural University,
Date of publication, distribution, etc. August 2021.
300 ## - PHYSICAL DESCRIPTION
Extent 57 leaves ;
Dimensions 28 cm. + 1 computer disc (4 3/4 in.)
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note This study aimed to establish the hypocholesterolemic potential of spray-dried yacon roots and okra leaves on cholesterol-fed mice. Eighteen white mice randomly assigned to six treatments were used to determine the effect of spray-dried yacon roots and okra leaf extracts on weight, feed intake, water intake, lipid profile, and histopathology of the liver. All animals were given a hypercholesterolemic diet for 28 days. Treatment 0 was assigned as the negative control group receiving only distilled water, whereas Treatment 1 was designated as the positive control group receiving 10 mg simvastatin. Treatments 2 and 3 were treated with 20 and 40 mg yacon extract via oral gavage, respectively. Okra leaf extract at 20 and 40 mg was given to the mice in Treatments 4 and 5, respectively. One-way ANOVA was used to analyze the data, with Tukey's HSD as a post-hoc test. The treatments were observed to significantly affect weight and feed intake of the hypercholesterolemic mice, whereas lipid profile parameters had no significant changes indicating that the dosages of spray-dried extracts of yacon and okra can reduce lipid parameters but only to a certain extent. In addition, histology of the liver showed significant changes and proved the potential of both treatments.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Guevarra, Eunice C.,
Relator term Adviser.
Holdings
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      Not for loan PSAU OLM PSAU OLM Dissertation, Theses 01/17/2023   UT G99 2021 UT12238 04/08/2025 04/08/2025 Theses