The study entitled "Frog Dissection Simulation Through Three Dimentional Modeling Using Mobile Device" aim to design and develop a 3D Model of a Frog Dissection using Android application. it aimed biology students and alternative method in learning dissection. Specifically, the system provides learning guide of frog's anatomy, provides virtual way of dissecting frog using 3D Model, and provides quiz assessment to test the student's knowledge. The system was developed using Unity software, a strong cross-platform game development 3D engine, Blender for 30 modeling, Adobe Photoshop for design, and C# as the programming language for the system's functionalities also information about frog dissection that was gathered in a laboratory manual to help students understand the structure and functions of organ systems and their specific functions. To study the problem and identify the flow and output of the software, the researchers employed Data Flow Diagrams (DFD), Context Diagrams, Use Case Diagrams, and System Flow Charts. In addition, the researchers employed a variety of approaches and instruments to gather information, including consultation, interviews, and online research. The methods aided the researchers in reaching a conclusion and determining the present issue confronting the Socale. The biology students and Instructors in the Department of Biology at Pampanga State Agricultural University who evaluated and assessed the functionality of the system had helped the researchers to conclude the study. The system had really helped learning more interactive and interesting. Students and instructors are satisfied with the application's overall appearance and performance and also the information's reliability and accuracy of each 3D Model of the Frog Dissection. Therefore, it was concluded that the study met all its objectives.